China Instrument Network Instrument R&D Recently, the Shenzhen Institute of Advanced Technology of the Chinese Academy of Sciences Li Penghui, Yu Xuefeng, Luo Yu and others have successfully developed a magnetically movable Raman enhanced (SERS) detection chip that has achieved a variety of environmental pollutants. The rapid detection of high sensitivity.
Related papers: Efficient Enrichment and Self-Assembly of Hybrid nanoparticles into Removable and Magnetic SERS Substrates for Sensitive Detection of Environmental Pollutants (Rapidly assembled self-assembly nanoparticle magnetically movable Raman detection chip and its application in sensitive detection of environmental pollutants Application ") was published in the international journal ACS Applied Materials & Interfaces. In addition, the team worked with the Guangdong Shenzhen Agricultural Product Quality and Safety Testing and Inspection Center to formulate the Shenzhen Standard "Rapid Detection of Malachite Green in Surface-enhanced Raman Spectroscopy in Aquaculture Water."
SERS detection technology has been widely used in food safety, life sciences, and environmental monitoring because of its advantages of label-free, high sensitivity, fast detection, and non-destructive. In general, the plasmon resonance effect of a noble metal nanostructure surface with a narrow gap of less than 10 nm can lead to a very effective SERS signal. Droplet volatilization self-assembly technology is a three-dimensional superlattice precious metal that can effectively construct such a narrow gap structure. Nanoarray method. Members of the research group Tang Siying, Li Penghui, and Li Yong used this technology to successfully prepare a magnetically movable SERS chip and achieved pesticides and environmental pollution such as malachite green, thiram, diquat, polycyclic aromatic hydrocarbons, etc. High sensitivity detection of molecules. Through the super-lubricated substrate constructed on the surface of the porous Teflon film, the gold nanorods and the magnetic Fe3O4 nanoparticles in the droplets are efficiently collected and self-assembled in the process of droplet volatilization, and can be detached from the substrate and in the magnetic field. A controllable three-dimensional superlattice structure. The SERS chip on the one hand due to the highly ordered array of gold nanorods to form a plasma superlattice structure has excellent SERS performance with high sensitivity and high detection limit, the detection limit can be as low as the nanomolar level; on the other hand, due to its Magnetic, and can be quickly separated from complex analytes, this SERS chip is suitable for rapid analysis and detection of environmental pollutants, and broaden the application of SERS chip in environmental monitoring.
In recent years, the research team has conducted in-depth research on SERS detection chip construction and SERS detection technology. It has made several breakthroughs in food safety and environmental pollutant detection, and applied for 5 patents for related inventions. These research results can not only realize the large-scale preparation of high-sensitivity and low-cost SERS detection chip, but also provide reliable fast optical detection technology for food safety testing and environmental monitoring.
The above research was funded by the National Natural Science Foundation of China, the Natural Science Foundation of Guangdong Province, and the basic layout project of Shenzhen Science and Technology Commission.
(Original title: Shenzhen Advanced Institute has successfully developed a magnetically movable Raman enhanced (SERS) detection chip)